【Chemical Name】 Chondroitin Sulphate Chicken
【Synonym】 poly-1(2/3)-n-acetyl-2-amino-2-deoxy-3-o-beta-d-glucopyranurosyl-4-(6)sulfonyl-d-galactose;chondroitinpolysulfate;chondroitinsulfates;chondroitinsulfuricacid;chondroitinsulfuricacids;chonsurid;CSO;(5ξ)-2-(Carboxyamino)-2-deoxy-3-O-β-D-glucopyranuronosyl-4-O-sulf o-α-L-arabino-hexopyranose
【CAS No】 9007-28-7,39455-18-0
【Molecular Formula】(C14H19NO14SNa2)n
【Molecular Weight】 463.36854
【Properties】Storage ConditionsStore at RT.
Solubility:water: 5 mg/mL Form:Powder
Color:White to off-white Water Solubility:Soluble in water.
【Specification】≥99
【Packing】25kg/drum
【Usage】
Used as pharmaceutical.
【Introduction】
Pharmacological Effects
Chondroitin sulfate is widely present in the cartilage tissues of humans and animals. Its medicinal preparations mainly contain two isomers: chondroitin sulfate A and chondroitin sulfate C. The content of chondroitin sulfate in the cartilage of animals varies with different species, ages, etc. Its pharmacological effects are as follows:
1. Chondroitin sulfate can remove lipids and lipoproteins from the blood in the body, clear cholesterol from the blood vessels around the heart, prevent and treat atherosclerosis, and increase the conversion rate of lipids and fatty acids in cells.
2. Chondroitin sulfate can effectively prevent and treat coronary heart disease. It has the effects of anti-atherosclerosis and anti-atheromatous plaque formation on experimental arteriosclerosis models; it increases the coronary artery branches or collateral circulation in atherosclerosis, and can accelerate the healing, regeneration and repair of myocardial necrosis or degeneration caused by experimental coronary arteriosclerosis or embolism.
3. It can increase the biosynthesis of cellular messenger ribonucleic acid (mRNA) and deoxyribonucleic acid (DNA), and has the effect of promoting cell metabolism.
4. Low anticoagulant activity. Chondroitin sulfate has a mild anticoagulant effect, and each 1mg of chondroitin sulfate A is equivalent to 0.45U of heparin in anticoagulant activity. This anticoagulant activity does not depend on antithrombin III; instead, it can exert anticoagulant activity through the fibrinogen system.
5. Chondroitin sulfate also has anti-inflammatory effects, can accelerate wound healing, and has anti-tumor effects, among others.