Chemical Name: Piperidinooxy（TEMPO）
Chemical Synonyms: TEMPO,FREERADICAL;TEMPO;2,2',6,6'-Tetramethylpiperidin-1-oxyl;2,2,6,6-TETRAMETHYLPIPERIDINOOXY,FREERADICAL;2,2,6,6-TETRAMETHYLPIPERIChemicalbookDINOXY;2,2,6,6-TETRAMETHYLPIPERIDINOXYFREERADICAL;2,2,6,6-TETRAMETHYL-4-PIPERIDINYLOXY;2,2,6,6-TETRAMETHYLPIPERIDIN-1-OXYLFREERADICAL
CAS No.: 2564-83-2
Molecular Formula: C₉H₁₈NO
Molecular Weight: 156.25 g/mol
TEMPO (CAS 2564-83-2), chemically known as 2,2,6,6-Tetramethylpiperidine 1-oxyl, is a stable nitroxide radical widely used as a catalyst for the oxidation of alcohols and as a free radical scavenger in organic synthesis and polymer chemistry. It enables highly selective oxidation of primary alcohols to aldehydes or carboxylic acids, and secondary alcohols to ketones, under mild conditions . With assay ≥98% (GC), it is suitable for laboratory research and industrial synthesis applications.
Parameter | Specification |
|---|---|
Product Name | TEMPO |
Synonyms | 2,2,6,6-Tetramethylpiperidine 1-oxyl; 2,2,6,6-Tetramethylpiperidinooxy; TEMPO free radical |
CAS Number | 2564-83-2 |
Molecular Formula | C₉H₁₈NO |
Molecular Weight | 156.25 g/mol |
Assay / Purity | ≥98% (GC) |
Appearance | Orange to red crystalline solid |
Melting Point | 36–40 °C |
Boiling Point | 193 °C |
Flash Point | 67 °C |
Storage | 2–8 °C, protected from light, under inert gas recommended |
Alcohol Oxidation Catalyst: Highly selective oxidation of primary alcohols to aldehydes or carboxylic acids, and secondary alcohols to ketones, using hypochlorite or other terminal oxidants .
Free Radical Scavenger: Used as a radical trapping agent, polymerization inhibitor, and stabilizer in polymer and materials research .
ESR/EPR Spectroscopy: Structural probe for electron spin resonance studies .
Organic Synthesis: Catalyzes oxidation of sulfides to sulfoxides, and other selective transformations .
Hazard Classification: Classified as Skin Corrosion/Irritation Category 1B (H314) and Serious Eye Damage (H318). Causes severe skin burns and eye damage .
Handling Precautions: Wear protective gloves, protective clothing, eye protection, and face protection. Use in a well-ventilated area (fume hood). Avoid inhalation of dust and contact with skin and eyes .
UN Number: UN3263 (Corrosive solid, acidic, organic, n.o.s.) .
Storage: Store at 2–8 °C. Keep container tightly closed in a dry place. Protect from light .
High Purity: Assay ≥98% (GC), suitable for catalytic and synthetic applications requiring consistent radical activity.
Well-Documented Reactivity: One of the most extensively studied nitroxide radicals, with established protocols for alcohol oxidation and radical trapping .
Batch Consistency: Controlled production ensures reproducible catalytic performance.
Full Documentation: COA and MSDS available upon request, including hazard classification and safe handling guidance.
Standard Packaging: 5 g / 25 g / 100 g / 500 g / 1 kg in amber glass bottles or aluminum foil bags, or customized packaging upon request.
Storage Conditions: Store at 2–8 °C in a tightly closed container, protected from light and moisture. Inert gas (argon) recommended for long-term storage .
Shelf Life: 24 months under proper storage conditions.