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Potassium 2-Hydroxy-4-Methoxybenzoate CAS 152312-71-5

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Chemical Name: Potassium 2-Hydroxy-4-Methoxybenzoate

Chemical Synonyms: Potassium Methoxysalicylate;Potassium 4-Methoxysalicylate;4MSK

CAS No.: 152312-71-5

Molecular Formula: C8H7KO4

Molecular Weight: 206.24

Product Overview

Potassium 2-Hydroxy-4-Methoxybenzoate (CAS 152312-71-5), commonly known as 4MSK (Potassium 4-Methoxysalicylate), is a high-purity cosmetic active ingredient widely used in skin-lightening and brightening formulations. It works by suppressing melanin production and promoting normal keratinocyte differentiation, offering a dual-action mechanism that distinguishes it from conventional tyrosinase inhibitors. With assay ≥99% and cosmetic-grade quality, it is suitable for serums, essences, creams, and lotions.

Key Specifications

Parameter

Specification

Product Name

Potassium 2-Hydroxy-4-Methoxybenzoate

Synonyms

4MSK; Potassium 4-Methoxysalicylate; Potassium Methoxysalicylate

CAS Number

152312-71-5

Molecular Formula

C₈H₇KO₄

Molecular Weight

206.24 g/mol

Assay / Purity

≥99% (HPLC)

Appearance

White to off-white crystalline powder

Grade

Cosmetic Grade

Melting Point

≥235 °C

Storage

Cool, dry place, protected from light and moisture

Applications

  • Skin Lightening & Brightening: Reduces melanin content and improves skin lightness in both pigmented and non-pigmented areas.

  • Hyperpigmentation Care: Suitable for formulations targeting dark spots, uneven skin tone, and post-inflammatory hyperpigmentation.

  • Keratinocyte Normalization: Promotes normal keratinocyte differentiation without the irritation associated with free salicylic acid.

  • Cosmetic Formulations: Recommended usage level up to 3% in serums, essences, creams, and lotions.

Why Choose This Product

  • Dual-Action Mechanism: Suppresses melanin production while supporting normal keratinocyte differentiation, offering advantages over single-action whitening agents.

  • Cosmetic-Grade Purity: Assay ≥99% with controlled heavy metals and microbial limits, suitable for leave-on skincare products.

  • Clinically Supported: 4MSK has been evaluated in clinical studies demonstrating significant skin-lightening effects.

  • Full Documentation: COA and MSDS available upon request for regulatory and formulation compliance.

Packaging & Storage

  • Standard Packaging: 1 kg / 5 kg / 25 kg in aluminum foil bags or fiber drums, or customized packaging upon request.

  • Storage Conditions: Store in a tightly closed container in a cool, dry place, protected from light and moisture.

  • Shelf Life: 24 months under proper storage conditions.

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